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To shed light on the interactions of the enzyme with the natural substrates, we docked flavan-3,3,4-triol ( 4 ) and flavan-3-on-4-ol ( 7 ) into the active pocket of the crystal structure of Pt GSTF8 obtained with ()-catechin ( 12 ) (Extended Data Fig

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10.1016/j.lfs.2016.02.029 [DOI] [PubMed] [Google Scholar] Barisic I., Balenovic D., Klicek R., Radic B., Nikitovic B., Drmic D., et al

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This finding is noteworthy as it parallels the protective effects of caffeine and paraxanthine, which has been shown to lower amyloid beta levels [10]