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10.3390/antiox9111031 41 GiddayJ

Beneficial effects of silibinin on serum lipids, bile acids, and gut microbiota in methionine-choline-deficient diet-induced mice

7A) has a molecular formula C 15 H 10 O 6 and a molecular weight of 286.24 g/mol

Some studies have found that M10 exerts higher activities in preventing UC through inhibiting necroptosis [143] however, it has also been demonstrated that the majority of M10 is metabolized to myricetin via fecal microbiota and that both compounds are mostly located in inflamed tissues, exerting their immunomodulatory actions [144]

This stress can cause a decrease in the production of inflammatory cytokines like TNF- and interleukins (such as IL-6, IL-10, and IL-1), ultimately leading to the death of these cells