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HDAC1 governs iron homeostasis independent of histone deacetylation in iron-overload murine models

Evidence suggests that prescription retinoid-containing products are the most likely candidate to lead to severe congenital irregularities

In terms of clinical application, the GPX4 agonist selenomethionine (Se-Met) upregulates GPX4 expression in a liver cancer model, and in combination with a PD-1 antibody, it significantly improves the complete response rate (CR) (183)