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Though the underlying cause may vary, symptoms are the result of overproduction of androgens typically of ovarian or adrenal origin, though, rarely the source may be tumoral or increased cutaneous sensitivity to androgens

Walker GS, Bauman JN, Ryder TF, Smith EB, Spracklin DK, Obach RS

In contrast, in microautophagy and CMA cargo is directly taken up by the lysosome, either through the invagination of the lysosomal membrane or by unfolding and translocation of proteins with a specific signal sequence (327, 332, 359)

Wang X, Gu Z, Huang Y, et al

doi:10.1016/j.cell.2013.12.010 Skouta R, Dixon SJ, Wang J et al (2014) Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models