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Acetylcholine is an important excitatory neurotransmitter of the peripheral nervous system

2.5.3 Regulation of Oxidative Stress Oxidative stress in the brain plays a key role in the development of PD (155, 156), and results from an imbalance between reactive oxygen species (ROS) and the ability to scavenge reactive intermediates (157)

TDP-43/HDAC6 axis promoted tumor progression and regulated nutrient deprivation-induced autophagy in glioblastoma

These GAD-associated syndromes, all characterized by abnormal synaptic neurotransmission, comprise the GAD antibody-spectrum disorders (GAD-SD) or SPS-SD since SPS remains the hallmark disease among all of them, although one or more of these disorders coexists in approximately 70% of patients with GAD65 neurological autoimmunity [3, 6,7,8,9, 30,31,32,33,34,35,36,37,38]

Deletion of Nox4 in the nuclei of alveolar epithelial cells significantly reduces intranuclear H 2 O 2 production (by over 80% compared with controls), thereby protecting mice from Pseudomonas aeruginosa -induced pneumonia injury