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Methods: The anti-senescence effects of PT were investigated in human dermal fibroblasts (HDFs) using models of UVB-induced acute oxidative stress and replicative senescence

Zhu F, Willette-Brown J, Song NY, Lomada D, Song Y, Xue L, et al

It is of some interest that liver tumors in chlordane-treated mice, including some hepatocellular carcinomas, were shown to regress upon cessation of treatment, suggesting that their tumor response was conditional upon continued exposure to chlordane (Malarkey et al

FGF23 acts in opposition to GH by increasing phosphaturia via suppression of Na-Pi 2a and 2c expression in proximal tubules and decreasing renal calcitriol synthesis, whereas it shares its calcium-sparing effects by enhancing renal calcium reabsorption in the distal tubule [81]

Pharmacological Basis of Therapeutics