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This caution is due to the potential of PT-141 to cause temporary rises in blood pressure

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Reconstitution: Add 2.0 mL bacteriostatic water 5 mg/mL Typical Dose Range: 2501000 mcg daily Measurement: 1 unit (U-100 syringe) = ~50 mcg Storage: Lyophilized: 20C Reconstituted: 28C (use within 12 weeks) Dosing & Reconstitution Guide Educational guide for reconstitution and daily dosing Standard / Gradual Titration (2 mL = 5 mg/mL) Maintenance : 500750 mcg 12 weekly (10-15 units) Administer via subcutaneous injection once daily during the initial 8-week tanning phase , then transition to 12 injections per week for maintenance to help sustain pigmentation