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VD was associated with a significant reduction in TGF-1 expression, as well as the activation of SMAD-2 and SMAD-3

Future research should focus on clinical trials to establish efficacy, improve bioavailability, and create standardized formulations of OSCs for cardiovascular disease prevention and management

For example, a study found that Bifidobacterium longum NCC3001 normalizes anxiety-like behavior and hippocampal brain-derived neurotrophic factor (BDNF) in mice with infectious colitis

[15] The last of the 20 common amino acids to be discovered was threonine in 1935 by William Cumming Rose, who also determined the essential amino acids and established the minimum daily requirements of all amino acids for optimal growth

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