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Lanosterol modulates TLR4-mediated innate immune responses in macrophages

Dankner M, Wang Y, Fazelzad R, Johnson B, Nebhan CA, Dagogo-Jack I, Myall NJ, Richtig G, Bracht JWP, Gerlinger M, Shinozaki E, Yoshino T, Kotani D, Fangusaro JR, Gautschi O, Mazieres J, Sosman JA, Kopetz S , Subbiah V, Davies MA, Groover AL, Sullivan RJ, Flaherty KT, Johnson DB, Benedetti A, Cescon DW, Spreafico A, Zogopoulos G, Rose AAN

Glutathione Detection Summary New Parts: BBa_K3206000, BBa_K3206001, BBa_K3206002, BBa_K3206003, BBa_K3206004, BBa_K3206005, BBa_K3206006, BBa_K3206007, BBa_K3206008, BBa_K3206009, Glutathione is a biomarker associated with Parkinson's disease

Biopanning identified a 12-mer linear peptide, DWSSWVYRDPQT, and two 7-mer cysteine-constrained peptides, CIGNSNTLC and CTVRTSAEC that bound FR in the context of the phage particle

Fifty microliters of the reaction mixture were collected every ~20 min and added to 50 L of a 50% acetic acid aqueous solution