The challenge is not whether GHK-Cu has biological activity (that is well-established) but whether that activity can be delivered to tissues at concentrations and durations sufficient to produce clinical effects beyond the skin surface
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The target protein was eluted with 20 mM HEPES pH 8.0, 150 mM NaCl, 0.025% DDM, 0.0025% CHS, and 2.5 mM desthiobiotin (IBA Lifesciences)