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GHK-Cu should be avoided during pregnancy or breastfeeding, in active cancer or untreated solid tumors, in Wilson's disease or other copper-handling disorders, and in known copper allergy

First, although GPER has been extensively studied in animal models (mice and rats), the phenotypes observed in these models may not fully replicate those observed in humans, thereby limiting the generalizability of the findings

Skin biopsy: a new tool for diagnosing peripheral neuropathy

The available scientific evidences are all equivocal of the fact that synuclein fibrillation consists of two distinct steps a) Nucleation or initiation of fibrillation and b) elongation of fibrillation

Mimics and models of glutathione peroxidase 2.1 Ebselen analogues as GPx mimics/models Synthetic selenium compounds with significant GPx activity have potential therapeutic applications (Figure 3)