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Notably, methionine-R-sulfoxide reductase B1 (MSRB1), a stereospecific enzyme that catalyzes the reduction of methionine-sulfoxide to methionine emerges as a prime candidate for mediating this redox cycling [36]

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Finally, there was one case of a mild adverse reaction (lethargy, decreased appetite) during Phase I, and that family decided not to continue into Phase 2

Moreover, there was no obvious early apoptotic cells, which basically ruled out the occurrence of apoptosis