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When this system becomes overwhelmed, cells, proteins, and DNA can suffer damage that accumulates over time

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Collectively, these compositional shifts implicate multiple functional pathways relevant to CHE, including short-chain fatty acid production (e.g., Lachnospiraceae , Eubacterium ) [72], inflammatory signaling and microbial product-related pathways (e.g., Enterobacteriaceae , Streptococcaceae ) [73], and ammonia or nitrogen metabolism (e.g., Clostridiales ) [74], rather than a single dominant mechanism

Dietary Lactobacillus plantarum supplementation decreases tissue lead accumulation and alleviates lead toxicity in Nile tilapia ( Oreochromis niloticus )

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