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Author response: We have altered the phrasing to read, Adult wildtype C57BL6/J mice were injected with TAM or matched dose (ml/kg) of vehicle (oil) for 5d. Reviewer 1 In regard to an issue raised by Reviewer 2 (below) I question whether the estrous cycle would need to be tracked

Benefits to Vitamin and Booster Shots Greater absorption rate to deliver nutrients more effectively than food or oral supplements Takes only seconds to inject into the body Minimal side effects and downtime Long-lasting effects Instant boost of energy with vitamins for energy Supports healthy immune function Enhances immune system health Why go generic when you can have a program tailored to your needs

This treatment is commonly considered for men who: Experience persistent fatigue or low energy Have difficulty absorbing B12 from oral supplements Want support for nerve and metabolic function Are seeking clinician-guided nutrient optimization Men receiving care at our North Overland Park location undergo a personalized evaluation to ensure Vitamin B12 injections align with their individual wellness goals

Its also not a substitute for a healthy lifestyle