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This research was supported by the Chung Shan Medical University, Taichung, Taiwan (Grant number FCU/CSMU 111-001 and CSH-2023-C-052 to L-YC, Y-CL, and H-CL), and the National Science and Technology Council, Taipei, Taiwan (Grant number NSTC 113-2314-B-038-032-MY2 to H-MC)

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The selectivity profile against related SAM-dependent methyltransferases has been characterized in the same publication series