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THC and CB1 agonists can reduce the release of presynaptic neurotransmitters and disrupt the long-term plasticity of hippocampal synapses 52,56

doi: 10.1097/MS9.0000000000003520 Kaye Alan D

Effects of p-aminophenol alone or in combination with the selective CB2 receptor antagonist SR144528 on lipopolysaccharide (LPS)-induced nitric oxide release