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Two further phase II trials (280, 281) with larazotide acetate failed in finding an improvement in intestinal permeability, whereas the last trial published (282) underlined possible usefulness in refractory CD, defined as malabsorption and continued villous atrophy on duodenal biopsies despite strict avoidance of gluten for a minimum of 12 months (283)

10.1016/j.bbamem.2006.07.007

There is a growing body o

GLP-1 receptor agonists modify gut motility, which affects bacterial populations

Central venous access devices also help lower the probability of local reactions by guaranteeing that the vaccine is administered correctly