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doi: 10.1007/s11845-023-03412-8 19 AvciKSarandlA

Given that aging is associated with a decline of mitochondrial functions along with the development of aging-related diseases, and given that the tissue and circulating levels of MOTS-c fall with age, it is compelling to hypothesize that declining MDP levels are also related to age-related metabolic deterioration

Men get urine infections too

As a result, these agents act together to cause additional oxidative damage, creating a never-ending chain reaction (also may be considered a feed-forward loop)