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High-Frequency Spinal Cord Stimulation Recenty published randomized crossover SENZA-PDN study with 216 participants proved that high-frequency 10-kHz spinal cord stimulation (SCS) significantly decreased pain severity and provided additional clinically meaningful improvements in a quality of life questionnaire and overall functioning for patients with peripheral DPN

Figure 1 In addition, to fully determine the impact of LA on renal dysfunction induced by FA, the direct evaluation of renal function was determined with the indicators as displayed in Supplementary Table 1, FA injection markedly decreased urine volume, glomerular filtration rate (GFR), and filtration fraction compared with control mice, but these indexes could be reversed partially by LA supplementation, without obvious difference between the two dose groups

Midtbo H, Kringeland E, Gerdts E, Ueland PM, Meyer K, Linde A, Ulvik A, Jonsson R, Tveit KS (2022) Biomarkers of inflammation and left ventricular remodelling in psoriasis patients treated with infliximab

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