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[42] The amplification of the cell surface receptor MET often drives resistance to anti-EGFR therapies in colorectal cancer

In addition to DNA synthesis, B12 is vital for energy production, as it acts as a cofactor for certain enzymes involved in cellular energy metabolism in the mitochondria

Using X-ray crystallography, they pinpointed the binding site for these molecules on the protein

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However, getting enough vitamin B-5 can ensure that your body is properly converting food into energy