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Du Z, Wang X, Zhang X, Gu Z, Fu X, Gan S, Fu T, Xie S, Tan W

In particular, using 3 different cell lines as digestion simulated models (AGS, Caco-2, and SW1353 cells), the authors demonstrated that a proprietary bromelain extract could decrease IL-8, COX-2, iNOS, and TNF- without affecting cell viability

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As will be discussed, one mechanism which may connect thiol-metal binding to oxidative stress-mediated toxicity is specific of Hg, the cysteinyl-glycine bound form of which is able to deplete glutathione reservoirs by a catalytic process [34]