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Figure 1 Figure 2 The patient underwent ultrasound-guided needle biopsy of the liver mass on 21 March 2023

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Further, such hydrogel according to the invention may be functionalized with a spacer carrying the same reactive functional group, for instance, amino groups may be introduced into the modified reactive biodegradable hydrogel by coupling a heterobifunctional spacer, such as suitably activated COOH-(EG) 6 -NH-fmoc, and removing the fmoc-protecting group