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Aging is associated with a progressive decline in mitochondrial function, characterized by reduced mitochondrial biogenesis, increased oxidative damage, and impaired mitochondrial dynamics [31]

146 It is estimated that the loss of unparasitised erythrocytes accounts for approximately 90% of the acute anaemia resulting from a single infection

cautious use is recommended in patients with milder forms of renal disease or renal impairment (3, 5)

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632 Nebivolol prevents disease progression in patients with DPN, probably through its dual effects as an antioxidant and NO enhancer