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demonstrated that MPP+-induced death of SH-SY5Y neuronal cells can be partially inhibited by both ferrostatin-1 and necrostatin-1 (Ito et al., 2017)

Patients with a proven indication for a PPI should continue to receive it in the lowest effective dose

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Compliance with ethics requirements We have obtained informed consent from all participants, and all processes involving human tissues in this study were approved by the Ethics Committee of the First Affiliated Hospital of Jinan University (approval number: KY-2021-092)