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Symptoms include: extreme tiredness, lack of energy, pins and needles, muscle weakness, depression and problems with memory, understanding and judgement

The mechanisms are well documented

One aspect of the invention pertains to the use of small molecule quinoline derived cations of Formula I for muscular therapy, wherein: R 1 is C 1-4 alkyl R 2 , R 3 , R 4 , and R 5 are independently selected from the group consisting of: H, C 1-4 alkyl, halogen-substituted C 1-4 alkyl, NR 9 R 10 , and CN R 6 is H or halogen R 7 is H, methyl, or NR 11 R 12 R 8 is H, C 1-4 alkyl, halogen-substituted C 1-4 alkyl R 9 , R 10 , R 11 , and R 12 are independently selected from H and C 1-4 alkyl

The capsules utilize a gastric-resistant (enteric-coated) shell designed to survive the acidic stomach environment and dissolve in the higher pH conditions of the small intestine

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