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In vitro GSH sensitivity and selectivity experiments The HT adducts were prepared by combining the HT protein (~50 M in PBS) with the respective TRaQ-G ligand (1.52 excess, stock solution 50 mM in DMSO) and rotating the resulting solution for 1 h at 20 C

swelling of the ankles or feet

--Glutathione helps to detox the liver, enhance immune system, metabolize toxins, repair wounds, and is a powerful antioxidant

Alternatively, enhancing antioxidant defenses by activating NRF2 or using mitochondria-targeted antioxidants provides a more selective strategy [222]

For instance, NATs are closely associated with the metabolism of aromatic amines (Minchin and Butcher, 2015