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Notably, low H4K12ac was previously shown to be associated with HR-deficiency in ovarian cancer patients (McDermott et al., 2020), further illustrating the translational potential of our work

It breaks down the sulfomucins into small organic metabolites that can then be used by hydrogenogenic bacteria, mainly Bacteroidetes and Firmicutes strains, as a source for hydrogen gas production through fermentation (Wolf et al., 2016)

The RNAi molecules usually include the short interfering RNAs (siRNAs), the short hairpin RNAs (shRNAs) and the artificial miRNAs, which need to be delivered to the cell via the viral vectors (e.g., adeno-associated viruses) to function as gene silencers (41)

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