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Similar content being viewed by others Introduction Cisplatin is a commonly used platinum-containing anticancer drug for various solid tumors, but its clinical application has been limited because of the onset of severe side effects such as peripheral and central neuropathies, renal insufficiency and sensorineural hearing loss

Nguyen, C

doi: 10.1016/S0960-9822(00)00742-9 223 Martins-FerreiraR.Calafell-SeguraJ.LealB.Rodrguez-UbrevaJ.Martnez-SaezE.MereuE.et al

As with Codeage, the intervals align with daily use quantities

Phase II Detoxification in the Liver Glutathione transferases (GST) conjugate GSH directly to endogenous and exogenous electrophilic compounds, including xenobiotics, carcinogens, and heavy metals