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Compared to healthy controls, the number of peripheral blood NKT cells is significantly reduced in patients with primary Sjgrens syndrome, but there is a considerable accumulation of NKT cells in the minor salivary glands of SS patients, correlated with the severity of sialadenitis, and high levels of IFN- secreted by NKT cells may exacerbate inflammation in the labial glands of SS patients (94, 95)

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2022 Oct 4:13:946871

doi: 10.1016/j.canep.2024.102550

Anderson, P