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Quinoline and its derivatives, which could chelate with iron, zinc, and copper, have the potential to improve cognition, reduce A deposition, and promote A degradation in AD animal models (Grossi et al., 2009

There was a significant increase in the phosphorylation state of ERK in transgene-positive mice compared with transgene-negative mice, suggesting that ERK is implicated in the proliferation of melanoma cells (80)

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The IC 50 parameter for protease inhibition could not be assessed due to the high hydrophobicity of the compounds and their precipitation in the assay buffer