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The CMV-promoter driven -catenin expression plasmid pbCAT, containing human -catenin cDNA with an activating S33Y mutation was provided by Dr

Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension

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This phase typically provides the clearest indication of whether the protocol is working for a given individual and condition