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This review encapsulates recent advancements in research, highlighting novel targets and agents, such as natural compounds, synthetic inhibitors, and clinical trial-stage candidates, all centered on ferroptosis strategies, to offer guidance for future therapeutic developments (Table 3)

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Taken together, our findings demonstrate that AF4 administration effectively modulated key components of the RAAS, reduced oxidative stress, and mitigated inflammatory responses in the DOCA-salt hypertensive model possibly by virtue of several bioactive peptides

Safety, side effects, and considerations Early animal studies show BPC 157 safety data as encouraging