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For systemic peptides like MOTS-c or SS-31 , the injection site matters less because the peptide enters systemic circulation regardless of where it is administered

According to emerging studies, resolution biology specialized lipid mediators (resolvins, protectins, maresins), Treg-derived cytokines, and vagus-nerve-dependent anti-inflammatory pathways that actively terminate harmful immune activity has a major effect on neuroprotection in PD

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