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Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine

In comparison with untreated MASH group, our study showed that administration of Mito and Pro, either alone or in combination, significantly reduced liver weight, liver index, liver function enzymes, blood glucose, serum insulin, and HOMA-IR as well as improved the dyslipidemia

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Here we demonstrate that PAT confers ferroptosis resistance to cancer cells by upregulating ferritin (FTH1/FTL) and sequestering intracellular iron

69 GibbsM