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A structural comparison of the wild-type AR bound to DHT and the agonist-converted AR-bicalutamide complex demonstrated that the sites that bind the A and B rings of DHT are similar to the sites bound by bicalutamide

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However, the role of this mechanism in cancer cachexia remains unclear and warrants further investigation

L-carnitine, a chemical compound widely present in red meat (and also some energy drinks), alters the composition of gut microbiota, leading to a potentially increased risk of heart disease

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