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Due to increasing life expectancy and an active, aging population, OA has become the leading cause of joint pain and age-related disability ( th leading cause of disabilities worldwide ( OA is a chronic, low-grade inflammatory, progressive joint disorder characterized by structural damage to one or more joints ( Figure 1 ) ( Figure 1 ) ( Figure 1 The course of OA is highly variable among individuals

He tries to convince her not to use drugs so much, because it's messing them up - he doesn't even know who she is anymore, because the person she used to be is lost underneath the haze of drugs