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1 Introduction Schizophrenia (SZ) is a chronic brain disorder characterized by genetic heterogeneity and neuropathological alterations, with high mortality rates ( Current evidence from genetics, molecular neuropathology, and clinical studies underscores the importance of immune factors in both the pathogenesis and treatment of schizophrenia ( Figure 1 )

It has also been demonstrated that NAD + can exacerbate high-fat diet (HFD)-induced lipid accumulation in mice through the SIRT1/AMPK/SREBP-1 signal pathway (Shehata et al

2022;8:eadc9317

Beyond energy and cognition, the nervous system and cardiovascular system rely heavily on B12 to maintain structural integrity and fluid dynamics

Cinnamon extract improves insulin sensitivity in the brain and lowers liver fat in mouse models of obesity