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2.10 Statistical methods All data in this study are reported as mean standard deviation

In preclinical work, MOTS-c is described as interfering with the folate cycle, leading to a build-up of AICAR (an AMP analog) that switches on AMPK [1] [2]

The cavitation effect of microbubbles under ultrasound stimulation creates temporary openings in tight junctions, enabling drug delivery without significant endothelial damage