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Brain Behav Immun (2022) 105:13948

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The mechanisms underlying the atherogenic and thrombogenic effects of TMAO include enhanced foam cell formation, reduced reverse cholesterol transport, and induction of platelet aggregation 9,10,12,15

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It also suppresses DCs: 2 mM butyrate blocks STING-dependent phosphorylation, reducing IFN- by 50% and undermining radiotherapy (76), as noted earlier