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Ginsenoside Rg3 inhibits renal cell carcinoma cell migration, invasion, colony formation, and tube formation and enhances apoptosis through promoting the DNA demethylation and histone acetylation

For lipid peroxide evaluation, cells were incubated for another 30 min after being stained with BODIPY 581/591 C11 probe (2.5 M)

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Several pivotal clinical trials have already demonstrated the superiority of combining anti-angiogenic agents and ICIs in various malignancies

The distribution and expression levels of ER and ER differ across various tissues, which underlies the diverse biological effects of estrogen (16)