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As the primary factors for the reduced anticancer effect 1) the reduced delivery and uptake of the anticancer agent, 2) the need for the conversion of molecular oxygen (O 2 ) into reactive oxygen species (ROS), 3) the preferred therapeutic effect against highly proliferating cells, which is reduced under hypoxic conditions, or 4) adaptation of the cancer cells by promoting cell survival and upregulating certain resistance pathways, has been suggested 1,2,3,4,5

L-Theanine may help promote a calm, focused mindset during stressful situations while also supporting important calming neurotransmitters like GABA and dopamine

Active targeting of dendrimers induces P-glycoprotein (P-gp) overexpression and apoptosis in multidrug-resistant cells (207)

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were found in 45 samples of BP after 3 days of storage condition along with the presence of mycotoxin DON (120 g/kg) and ZEN (280 g/kg) (204)