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Its anti-inflammatory, and is protective to the cells in our bodies

Accumulating evidence suggests that overstimulation of glutamate receptors, impaired mitochondrial functions, and oxidative stress are interconnected events that lead to oxidative neuronal injury in patients with autism [81, 82]

In lung cancer cell lines, the expression of FSP1 is negatively correlated with the sensitivity to RSL3, ML162, or ML210 (GPX4 inhibitors) [68]

Knockout of either Grx5 or Grx3 leads to iron accumulation in cells [31,136,137] , impaired FeS cluster biosynthesis [138] , and deregulated iron homeostasis via IRPs [31,137,139] (Figure 4)