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Of note, projection of the first two PCs (PC1 and PC2), which covered maximum variations, showed a considerable compact cluster distribution (centered between 50 to + 50 plane) for the residual motion in the mh-Tyr structure docked with all the ligands during 100 ns simulation, except in mh-Tyr-EC complex (centered between 100 to + 100 plane), by comparison to apo-mh-Tyr (centered between 50 to + 50 plane) (Fig

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The omnipresence of these enzymes in all types of organisms highlights an ancient origin as well as fundamental functions preserved during evolution

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However, this result is expected considering the very high activity of glutaredoxins as deglutathionylating enzymes and a decreased GSSR concentration neither excludes mechanism (ii) or (iii) from Fig

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it's a vital part of understanding how our nutritional choices interact with the complex, rhythmic fluctuations of female hormones

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