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Porporato et al

Total ornithine, putrescine, spermidine, and spermine in ALDH18A1 KO PDLCs cells fed 15 N 1 -glutamine for 24 h

The elimination half-life is 18 to 24 h

Inflammation Hyperglycemia, metabolic disorder and abnormal hemodynamics can cause cellular injury and induce the inflammatory mediators, including tumor necrosis factor- (TNF-), interleukin-6 (IL-6), chemokines and adhesion molecules, etc