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(2016) Madison Memory Study: A randomized, double-blinded, placebo-controlled trial of apoaequorin in community-dwelling, older adults

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doi: 10.2741/1268

A study published in the Proceedings of the National Academy of Sciences found that aging is associated with a 47% decrease in the catalytic subunit (GCLC) and a 52% decrease in the modulatory subunit (GCLM) of glutamate-cysteine ligase, the rate-limiting enzyme for glutathione production