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Characterized by progressive axonopathy, sensory deficits, and chronic pain, the pathophysiology of diabetic neuropathy includes chronic hyperglycemia-induced oxidative stress, neuroinflammation, and dysregulated neurotrophic signaling (Sandireddy et al., 2014

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Unlike other drugs for AD, this potent nootropic does not only impede the progression of the disease but it actually repairs the damage in the synapse (junction) between neurons

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Among the non-competence-associated genes (Figure 6B), CCNA2 was upregulated in the HS control group compared to the NT control ( p = 0.0149 ), while supplementation of QUE and SFN downregulated CCNA2 expression as compared to the HS control ( p = 0.0464 and 0.0047, respectively)