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Description

Delivered intravenously, absorption bypasses the digestive system entirely

It is also used as an antidote to paracetamol (acetaminophen) poisoning and found to be effective for the prevention of cardiotoxicity by doxorubicin and haemorrhagic cystitis from oxazaphosphorines

Epub 2023/10/05

95 Furthermore, FXR sulfation, a post-translational modification influenced by endogenous hepatic cystathionine lyase/hydrogen sulfide, promotes FXR activity, thereby improving MASLD