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Similarly, SGLT-2is, also referred to as gliflozins, represent another class of anti-hyperglycemic agents currently used in T2D treatment with favorable effects on body weight

doi: 10.1016/s0014-4800(03)00015-7

Activated macrophage induced the expression of IFN- and TNF- cytokines, improving NADPH oxidase activity resulting in ROS production, such as oxygen-free radicals (O 2 ) superoxide