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In descending order, the medications used included serotonin-norepinephrine reuptake inhibitors (used by 182 patients), gabapentin (155 patients), tricyclic antidepressants (134 patients), trazodone (59 patients), pregabalin (46 patients), muscle relaxants (45 patients), montelukast (26 patients), -blockers (21 patients), aripiprazole (12 patients), histamine 1 or histamine 2 blockers (11 patients), naltrexone (8 patients), amphetamine- or methylphenidate-based stimulants (8 patients), midodrine (7 patients), fludrocortisone (6 patients), non-amphetamine stimulants (4 patients), pyridostigmine (4 patients), -blockers (1 patient), and droxidopa (1 patient)

Another myokine, myostatin (MSTN), can cause muscle atrophy, but plasma Mstn concentrations negatively correlate with the development of the cachexia phenotype in colorectal or lung cancer patients

Acetylcholinesterase inhibition in patients with orthostatic intolerance

The exclusion criteria were: patients suffering from lung disease except extensive bronchiectasis, such as cystic fibrosis, and pulmonary fibrosis