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IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos

Strong CYP3A inhibitors (such as ketoconazole, itraconazole, and ritonavir) would be expected to increase orforglipron exposure, potentially necessitating dose adjustment

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It may take more than a month to feel pain alleviation after this operation